Related Experiment Video
Updated: Jun 27, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Early Quality-of-Life Changes in Mild Traumatic Brain Injury: A Prospective Study
Mulyadi Mulyadi1, Susilo Harianto, Santo Imanuel Tonapa
1College of Nursing, Kaohsiung Medical University, Kaohsiung, Taiwan (Dr Mulyadi, Mr Tonapa, and Dr Lee); School of Nursing, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia (Dr Mulyadi); and Faculty of Nursing (Mr Harianto) and Faculty of Vocational Studies (Mr Harianto), Airlangga University, Surabaya, Indonesia.
Background:
Postinjury symptoms and decreased quality of life are common after mild traumatic brain injury. However, few studies have examined how soon, after injury, these changes dissipate.
Objectives:
This study aimed to compare changes in postconcussion symptoms, posttraumatic stress, and illness representations and identify predictors of health-related quality of life before and 1 month after hospital discharge for mild traumatic brain injury.
Methods:
A prospective, multicenter, correlational design was used to measure postconcussion symptoms, posttraumatic stress, illness representations, and health-related quality of life. The survey was administered to 136 patients with mild traumatic brain injury between June 2020 and July 2021 at three hospitals in Indonesia. Data were collected at discharge and 1 month later.
Results:
Compared with before hospital discharge, data collected 1 month after discharge showed that patients experienced reduced postconcussion symptoms, posttraumatic stress, better illness perceptions, and quality of life. Those with postconcussion symptoms (β =-.35, p < .001), more posttraumatic stress symptoms (β =-.12, p = .044), more identity symptoms (β = .11, p = .008), worsened personal control (β =-.18, p = .002), worsened treatment control (β =-.16, p = .001), and negative emotional representations (β =-.17, p = .007) were significantly related to worsened health-related quality of life.
Conclusion:
This study shows that within 1 month of hospital discharge, patients with mild traumatic brain injury had decreased postconcussion symptoms, posttraumatic stress, and improved illness perceptions. Efforts to impact mild brain injury quality of life should focus on inhospital care to optimize the transition to discharge.
More Related Videos
04:54Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion
Published on: April 19, 2024
08:36Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025