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COMPARISON OF INTRAMUSCULAR VERSUS INTRAVENOUS KETAMINE FOR SEDATION IN CHILDREN UNDERGOING MAGNETIC RESONANCE

Jasim M Salman1, Jasim N Al-Asadi2, Husham H Abdul-Ra'aoof3

  • 1COLLEGE OF MEDICINE, UNIVERSITY OF BASRAH, BASRAH, IRAQ.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|March 8, 2023
PubMed

Insights

Intramuscular ketamine provided better sedation success and shorter scan times for pediatric brain MRI compared to intravenous ketamine. This method is more appealing for certain pediatric sedation needs.

Area of Science:

  • Pediatric Radiology
  • Anesthesiology
  • Pharmacology

Background:

  • Sedation is crucial for pediatric brain MRI to ensure image quality and patient safety.
  • Ketamine is a commonly used sedative agent in pediatric procedural sedation.

Purpose of the Study:

  • To compare the efficacy of intramuscular (IM) versus intravenous (IV) ketamine for sedation in children undergoing brain MRI.
  • To evaluate sedation success rates, scan times, and procedural interruptions between IM and IV ketamine administration.

Main Methods:

  • A randomized study comparing 1.5 mg/kg IV ketamine versus 4 mg/kg IM ketamine in children requiring elective brain MRI.
  • All patients received supplementary midazolam intravenously prior to positioning.
  • Monitoring included pulse rate, oxygen saturation (SpO2), and respiratory patterns.

Main Results:

  • Intramuscular ketamine demonstrated a significantly higher success rate for sedation with the first dose compared to the IV group.
  • Children receiving IM ketamine had significantly shorter scan times and lower rates of scan interruption and repeat.
  • Technician satisfaction with sedation was significantly higher in the IM ketamine group (98.1%) versus the IV group (80.8%).

Conclusions:

  • Intramuscular ketamine offers a superior sedative success rate and reduced scan duration compared to intravenous administration for pediatric brain MRI.
  • IM ketamine is a more appealing option for sedation in specific pediatric imaging scenarios, enhancing efficiency and patient management.
Abstract

Keywords:
IntramuscularIntravenousKetamineMRIScan time

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