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Published on: January 17, 2011
The effects of general anesthesia on upper respiratory tract infections in children
1Department of Anesthesiology, University of Michigan Medical Center, Ann Arbor 48109.
Insights
Children with uncomplicated upper respiratory tract infections (URIs) undergoing myringotomy surgery showed no increased risk of respiratory complications. Anesthesia and surgery even reduced the duration and prevalence of URI symptoms in these pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Respiratory Medicine
- Otolaryngology
Background:
- Upper respiratory tract infections (URIs) are common in children.
- The impact of URIs on perioperative respiratory complications in pediatric patients undergoing elective surgery remains a concern.
- Myringotomy is a frequent pediatric surgical procedure.
Purpose of the Study:
- To investigate the prevalence of perioperative respiratory complications and symptomatology in pediatric patients with URIs undergoing myringotomy.
- To compare complication rates between children with and without URIs.
- To assess the effect of general anesthesia and surgery on URI symptoms.
Main Methods:
- Prospective cohort study of 489 pediatric patients undergoing myringotomy.
- Anesthesia administered via face mask using halothane N2O/O2.
- Data collected from anesthesia/recovery records and standardized questionnaires.
- Comparison with a matched group of non-anesthetized controls.
Main Results:
- No significant difference in perioperative complications between asymptomatic children (1.23%), symptomatic children meeting URI criteria (1.28%), and symptomatic children not meeting criteria (2.38%).
- Pediatric patients receiving anesthesia and surgery experienced significantly fewer and shorter-lasting respiratory symptoms compared to controls.
- No increased morbidity observed in children with uncomplicated URIs not requiring tracheal intubation.
Conclusions:
- Acute uncomplicated URIs do not increase perioperative morbidity in pediatric patients undergoing myringotomy without tracheal intubation.
- General anesthesia and myringotomy surgery may lead to a decrease in the prevalence and duration of respiratory symptoms in children.
- Current findings support proceeding with minor elective surgeries in pediatric patients with stable, uncomplicated URIs.
Abstract:
A prospective cohort study of 489 pediatric patients was performed to investigate the prevalence of perioperative respiratory complications and symptomatology in children presenting for myringotomy with upper respiratory tract infections (URIs). All children undergoing myringotomy received halothane N2O/O2 anesthesia administered via face mask. Information on complications and respiratory symptoms was obtained from the anesthesia and recovery room records, and by standardized questionnaire. There were no significant differences in perioperative complications between asymptomatic children (1.23%), symptomatic children fulfilling predetermined URI criteria (1.28%), and symptomatic children that did not fulfill the URI criteria (2.38%). In addition, the prevalence and duration of respiratory symptoms was significantly less in children having received anesthesia and surgery than in a matched group of non-anesthetized controls who did not have surgery. Results from this study suggest that there is no increased morbidity for children presenting at minor surgery with acute uncomplicated URIs and who did not require tracheal intubation. In addition, the administration of general anesthesia and surgery to this group of patients was followed by a decrease in both the appearance and duration of a number of respiratory symptoms.
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