Risk Factors for Symptomatic Recurrence after Laparoscopic Adenomyomectomy: A 3-Year Follow-up.

Area of Science:

• Gynecology
• Surgical Oncology
• Reproductive Medicine

Background:

• Adenomyosis is a common gynecological condition.
• Laparoscopic adenomyomectomy is a surgical option for adenomyosis.
• Understanding recurrence factors is crucial for patient management.

Purpose of the Study:

• To identify clinical risk factors for symptomatic recurrence of adenomyosis.
• To evaluate factors influencing recurrence after laparoscopic adenomyomectomy.
• To provide insights for improving post-surgical outcomes in adenomyosis patients.

Main Methods:

• Retrospective study design.
• Inclusion of 149 patients undergoing laparoscopic adenomyomectomy.
• Analysis of preoperative, intraoperative, and postoperative data, including recurrence and follow-up information.

Main Results:

• Concomitant ovarian endometrioma was a significant risk factor for recurrence (HR, 2.06).
• Postoperative hormonal suppression significantly reduced recurrence risk (HR, 0.30).
• Older age at surgery (≥40 years) was associated with a lower risk of recurrence (HR, 0.46).

Conclusions:

• Concomitant ovarian endometrioma is a key risk factor for adenomyosis recurrence post-laparoscopic adenomyomectomy.
• Postoperative hormonal suppression and older age at surgery are protective factors against recurrence.
• These findings can inform clinical practice and patient counseling regarding adenomyosis management.