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Published on: May 15, 2014
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[Monkeypox virus: emerging of an old neglected virus]
Virologie (Montrouge, France)
|March 9, 2023
Summary
Monkeypox (simian orthopoxvirosis) cases emerged globally in 2022, highlighting this neglected Orthopoxvirus (OPXV). This review focuses on the Monkeypox virus (MPXV) outbreak and its scientific context.
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Context:
- Global emergence of simian orthopoxvirosis (monkeypox) in non-endemic countries since April 2022.
- Monkeypox virus (MPXV), an Orthopoxvirus (OPXV) endemic in Africa since 1958, has gained prominence.
- MPXV's classification as a Microorganism and Toxin (MOT) due to its relation to smallpox virus.
Purpose:
- To provide a comprehensive review of Orthopoxvirus (OPXV) knowledge.
- To specifically address the Monkeypox virus (MPXV) responsible for the 2022 outbreak.
- To inform research and public health strategies regarding MPXV.
Summary:
- The 2022 global outbreak of monkeypox (simian orthopoxvirosis) has brought the Monkeypox virus (MPXV) to international attention.
- MPXV, a member of the Orthopoxvirus (OPXV) genus, has been endemic in parts of Africa for decades.
- Its potential for misuse and laboratory accidents, coupled with strict biosafety regulations, complicates research efforts.
Impact:
- Increased awareness and understanding of a previously neglected infectious disease.
- Facilitation of targeted research into MPXV transmission, pathogenesis, and therapeutics.
- Informed public health responses to the ongoing global outbreak.
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