Impact of the 2018 UNOS Heart Transplant Policy Changes on Patient Outcomes

Neil S Maitra1, Samuel J Dugger1, Isabel C Balachandran2

  • 1Baylor College of Medicine, Department of Medicine, Houston, Texas, USA.

JACC. Heart Failure
|March 9, 2023
PubMed

Insights

The 2018 United Network for Organ Sharing heart allocation policy improved heart transplant efficiency by better stratifying candidates. This led to significant shifts in practices and patient outcomes, warranting further review.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Public Health Policy

Background:

  • The United Network for Organ Sharing (UNOS) revised its heart allocation policy in 2018, moving from a 3-tier to a 6-tier system.
  • This change was prompted by increasing numbers of critically ill heart transplant candidates and extended waitlist times.
  • The policy aimed to improve candidate stratification, reduce wait times for high-priority patients, and standardize criteria for common cardiac conditions.

Purpose of the Study:

  • To review emerging trends in US heart transplantation practices and patient outcomes after the 2018 UNOS policy implementation.
  • To analyze the impact of the new policy on various aspects of heart transplantation.
  • To identify areas for future policy modifications.

Main Methods:

  • Review of literature and data pertaining to heart transplantation in the United States post-2018.
  • Analysis of shifts in candidate listing practices, waitlist dynamics, and donor characteristics.
  • Evaluation of changes in post-transplantation outcomes and the use of mechanical circulatory support.

Main Results:

  • Significant changes observed in heart transplant practices, including listing patterns and waitlist mortality.
  • Alterations noted in donor heart characteristics and post-transplantation outcomes.
  • Shifts in the utilization of mechanical circulatory support devices.

Conclusions:

  • The 2018 UNOS heart allocation policy has led to notable changes in heart transplantation practices and patient outcomes.
  • Ongoing monitoring and analysis are crucial to understand the long-term effects of the policy.
  • Further modifications may be necessary to optimize the allocation of donor hearts and improve patient survival.

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
30
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
445
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
43
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
49
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
20