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Updated: Aug 7, 2025

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Intestinal obstruction secondary to Brunner's glands hyperplasia
Daniel Aparicio-López1, Javier Cuadal Marzo2, Leticia Ollero Domenche3
1Cirugía General y Aparato Digestivo, Hospital Universitario Miguel Servet, España.
Abstract:
Brunner's gland hyperplasia constitutes 10.6% of benign tumors of the duodenum, with an incidence of 0.008%. It is usually an incidental finding during endoscopy or imaging tests as they are small and asymptomatic. In the case of symptomatic tumors, resection of the lesion is indicated. In lesions ≤2 cm, endoscopic resection can be chosen, reserving surgery for larger lesions or endoscopically inaccessible ones. We present the case of a patient with a history of vomiting and hyporexia of months of evolution who presented peptic ulcer perforation and underwent surgery. During follow-up, she presented intestinal obstruction due to pyloric stenosis. Given the impossibility of ruling out a neoplastic process with certainty in diagnostic tests, surgical resection (antrectomy) was decided with an anatomopathological finding of Brunner's gland hyperplasia.
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