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Updated: Aug 7, 2025

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
Published on: April 5, 2016
Conservative Bladder Management and Medical Treatment in Chronic Spinal Cord Injury Patients.
Hueih Ling Ong1, I-Ni Chiang2, Lin-Nei Hsu3
1Department of Urology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-Yi 622, Taiwan.
Non-surgical management for neurogenic lower urinary tract dysfunction (NLUTD) in spinal cord injury (SCI) patients involves safe, minimally invasive treatments. Further research is needed for novel, long-term therapies to improve quality of life and preserve kidney function.
Area of Science:
- Urology
- Neuroscience
- Rehabilitation Medicine
Background:
- Neurogenic lower urinary tract dysfunction (NLUTD) is a common complication in chronic spinal cord injury (SCI) patients.
- Management aims to achieve continence, enhance quality of life, prevent infections, and preserve renal function.
Purpose of the Study:
- To review current non-surgical management strategies for NLUTD in SCI patients.
- To provide updated knowledge on minimally invasive, safe, and efficacious bladder management approaches.
Main Methods:
- Categorization of bladder management into storage and voiding dysfunction.
- Review of available data on current treatment modalities.
- Emphasis on the importance of regular renal sonography and video urodynamics.
Main Results:
- Current non-surgical approaches are minimally invasive, safe, and efficacious.
- Annual renal sonography and regular video urodynamics are crucial for monitoring.
- There is a lack of high-quality evidence and novel treatments for NLUTD.
Conclusions:
- Effective management of NLUTD in SCI requires a multidisciplinary approach.
- There is a need for more research into novel, minimally invasive treatments with prolonged efficacy.
- Collaboration between urologists, nephrologists, and physiatrists is essential for optimal patient care.
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The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...

