Efferent projections from posteroventral cochlear nucleus to lateral superior olive in guinea pig

Phaseolus vulgaris leucoagglutinin (PHA-L), a kidney bean lectin used as an anterograde tracer, was iontophoretically injected into the posteroventral cochlear nucleus (PVCN) of guinea pigs. PHA-L-labeled fiber segments and their terminal specializations were observed within the ipsilateral lateral superior olive (LSO) thereby establishing the existence of an efferent neural pathway from PVCN to this nucleus. Furthermore, the pathway is topographically organized with dorsal regions of PVCN projecting to the medial limb and ventral regions projecting to the lateral limb of LSO.