Related Experiment Video
Updated: Aug 7, 2025

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Remote Cardiovascular Hypertension Program Enhanced Blood Pressure Control During the COVID-19 Pandemic
Simin Gharib Lee1, Alexander J Blood1, Christopher P Cannon1,2
1Division of Cardiology, Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA.
Insights
The COVID-19 pandemic saw a remote hypertension management program significantly improve blood pressure (BP) control. This adaptable program enhanced patient outcomes despite healthcare disruptions, highlighting the potential of remote care.
Area of Science:
- Cardiology
- Public Health
- Health Informatics
Background:
- The COVID-19 pandemic disrupted traditional healthcare delivery, leading to reduced blood pressure (BP) assessments.
- Existing remote hypertension management programs faced challenges in effectiveness and adaptability during the pandemic.
Purpose of the Study:
- To analyze the impact of the COVID-19 pandemic on the effectiveness and adaptability of a remote hypertension management program.
- To evaluate changes in blood pressure control among patients managed remotely before and during the pandemic.
Main Methods:
- A retrospective observational analysis of 1256 patients (605 pre-pandemic, 651 during pandemic) in a remote hypertension management program.
- Utilized an evidence-based clinical algorithm, adapted during the pandemic, managed by a multidisciplinary team.
- Compared blood pressure control rates, home BP readings, and program engagement metrics between pre-pandemic and pandemic periods.
Main Results:
- The rate of achieving goal blood pressure (BP) significantly improved to 94.6% during the pandemic from 75.8% prepandemic (P<0.0001).
- Mean home BP fell approximately 16/9 mm Hg in both periods, with faster BP control maintenance during the pandemic (median 11.8 vs. 19.6 weeks).
- Increased patient engagement observed during the pandemic, with more frequent monthly calls (8.2 vs. 3.1) and home BP recordings (32.4 vs. 18.9).
Conclusions:
- A remote hypertension management program successfully adapted to pandemic challenges, demonstrating improved BP control and increased home BP monitoring.
- The program's adaptability and effectiveness suggest a transformative potential for hypertension management and care delivery.
- Remote management strategies are crucial for maintaining and improving cardiovascular health outcomes amidst healthcare disruptions.
Abstract:
Background The COVID-19 pandemic disrupted traditional health care; one fallout was a drastic decrease in blood pressure (BP) assessment. We analyzed the pandemic's impact on our existing remote hypertension management program's effectiveness and adaptability. Methods and Results This retrospective observational analysis evaluated BP control in an entirely remote management program before and during the pandemic. A team of pharmacists, nurse practitioners, physicians, and nonlicensed navigators used an evidence-based clinical algorithm to optimize hypertensive treatment. The algorithm was adapted during the pandemic to simplify BP control. Overall, 1256 patients (605 enrolled in the 6 months before the pandemic shutdown in March 2020 and 651 in the 6 months after) were a median age of 63 years old, 57% female, and 38.2% non-White. Among enrolled patients with sustained hypertension, 51.1% reached BP goals. Within this group, rates of achieving goal BP improved to 94.6% during the pandemic from 75.8% prepandemic (P<0.0001). Mean baseline home BP was 141.7/81.9 mm Hg during the pandemic and 139.8/82.2 prepandemic, and fell ≈16/9 mm Hg in both periods (P<0.0001). Maintenance during the pandemic was achieved earlier (median 11.8 versus 19.6 weeks, P<0.0001), with more frequent monthly calls (8.2 versus 3.1, P<0.0001) and more monthly home BP recordings per patient (32.4 versus 18.9, P<0.0001), compared with the prepandemic period. Conclusions A remote clinical management program was successfully adapted and delivered significant improvements in BP control and increased home BP monitoring despite a nationally observed disruption of traditional hypertension care. Such programs have the potential to transform hypertension management and care delivery.
Related Concept Videos
Hypertension and Regulation of Blood Pressure
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension V: Nursing Management
Factors affecting Blood pressure
Physiological Factors:
Hypertension II: Pathophysiology
Hypertension I: Introduction

