Related Experiment Video
Updated: Aug 7, 2025
08:47
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
2.5K
Allergen-specific immunotherapy and COVID-19: What happened?
Fabiana Furci1,2, Bianca Olivieri3, Laura Benda4
1Asthma Centre and Allergy Unit, University of Verona and Verona University Hospital, Verona, Italy.
Allergologia Et Immunopathologia
|March 14, 2023
Summary
COVID-19 did not significantly impact adherence to sublingual immunotherapy (SLIT) for allergic rhinitis and asthma. Treatment adherence declined independently, even before the pandemic, indicating other factors influence patient compliance.
Area of Science:
- Allergy and Immunology
- Respiratory Medicine
- Clinical Pharmacology
Background:
- COVID-19 pandemic disrupted chronic disease management, including allergen-specific immunotherapy.
- Assessing treatment adherence is crucial for managing allergic rhinitis and mild asthma.
Purpose of the Study:
- To evaluate adherence to sublingual immunotherapy (SLIT) in allergic rhinitis and mild asthma patients during the COVID-19 pandemic.
- To compare adherence rates before and during the pandemic.
Main Methods:
- Retrospective observational study at Verona University Hospital (2017-2021).
- Analysis of 5-grass-pollen 300 IR SLIT prescription and collection data.
- Comparison of treatment adherence in naive patients pre-COVID (2017-2019) and during COVID (2019-2021).
Main Results:
- Patient numbers starting SLIT treatment in 2017 were 264, decreasing to 181 (2018) and 135 (2019).
- Patient numbers starting SLIT treatment in 2019 were 226, decreasing to 139 (2020) and 102 (2021).
- Adherence rates showed a declining trend in both pre-pandemic and pandemic periods.
Conclusions:
- COVID-19 did not appear to influence adherence to sublingual immunotherapy (SLIT).
- Adherence to SLIT demonstrated an independent decline prior to and during the COVID-19 pandemic.
Related Concept Videos
02:06Allergic Reactions
28.1K
Overview
28.1K
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
374
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
374
00:42Cross-reactivity
31.4K
Overview
31.4K
01:27Allergic Drug Reactions
909
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
909
01:30Hypersensitivities
849
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
849
01:20Asthma: Pathogenesis and Management
496
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
496