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Hepatotoxicity of mebendazole. Relationship with serum concentrations of the drug
1Secteur de Gastroentérologie, Institut de Médecine, Hôpital de Bavière, Liège, Belgique.
Gastroenterologie Clinique Et Biologique
|October 1, 1987
Abstract:
We report the case of a 47-year-old female patient, suffering from multiple hydatid cysts of the liver, in whom hepatitis developed after mebendazole treatment. Clinical manifestations of hypersensitivity were absent. A correlation was found between serum mebendazole concentrations and the degree of cytolysis; this is compatible with a direct hepatotoxic effect of mebendazole.