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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: Aug 6, 2025

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication

Published on: September 20, 2016

A synthetic tumour microenvironment

Akhilesh K Gaharwar^1,2, Irtisha Singh^3,4,5

¹Department of Biomedical Engineering, College of Engineering, Texas A&M University, College Station, TX, USA. gaharwar@tamu.edu.

Nature Materials

|March 17, 2023

Summary

No abstract available in PubMed .

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