Spin and fragility in anaesthesia studies: when sirens sing into anaesthetists' ears
Marcelo Gama de Abreu1, Marcus J Schultz2, Ary Serpa Neto3
1Department of Outcomes Research, Cleveland, OH, USA; Department of Intensive Care and Resuscitation, Cleveland, OH, USA; Department of Cardiothoracic Anesthesiology, Cleveland Clinic, Cleveland, OH, USA; Department of Anesthesiology and Intensive Care, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.
Abstract:
Spin and fragility are common in randomised controlled trials published in anaesthesia journals. Staying with the facts and addressing only the primary endpoint in the conclusion of clinical research reports might help reduce spin. Routinely reporting the fragility index, in turn, could deliver information about robustness, enhancing the transparency of positive dichotomous results. It is in the best interest of clinical research that authors, reviewers, and journals come together to reduce spin and address the fragility of randomised controlled trials.
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