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Racial and Ethnic Disparities in Research and Clinical Trials

Nicole C Syder1, Nada Elbuluk1

  • 1Department of Dermatology, Keck School of Medicine, University of Southern California, 830 South Flower Street, Ste 100, Los Angeles, CA 90017, USA.

Dermatologic Clinics
|March 18, 2023
PubMed

Insights

Clinical trials need diverse participants for generalizable results. Many dermatology studies lack racial/ethnic diversity and reporting, requiring improved recruitment efforts for equitable medical research.

Area of Science:

  • Medical research
  • Clinical trial methodology
  • Dermatology

Background:

  • Clinical trials are crucial for evaluating treatment safety and efficacy.
  • Generalizability of trial results depends on participant diversity reflecting national/global populations.
  • Dermatology studies often lack racial/ethnic diversity and fail to report minority enrollment data.

Purpose of the Study:

  • To review the challenges and importance of diversity in clinical trials.
  • To highlight the deficit in racial/ethnic diversity and data reporting in dermatology studies.
  • To discuss reasons for underrepresentation and suggest improvements.

Main Methods:

  • Literature review of dermatology clinical trials.
  • Analysis of diversity metrics and reporting practices.
  • Discussion of factors influencing minority participation.

Main Results:

  • A significant number of dermatology studies exhibit insufficient racial/ethnic diversity.
  • Data on minority recruitment and enrollment are frequently missing.
  • Multiple factors contribute to these disparities in clinical trial participation.

Conclusions:

  • Improving diversity in clinical trials is essential for equitable healthcare.
  • Current efforts to enhance diversity in dermatology studies are insufficient.
  • Sustained and meaningful changes in recruitment and reporting are necessary.
Keywords:
Clinical trialsDermatologyDiversityEthnic skinHealth disparitiesHealth equityResearchSkin of color

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