Agminated Halo Nevus: A Novel Presentation

Area of Science:

• Dermatology
• Pathology
• Oncology

Background:

• Halo nevus is a benign melanocytic nevus characterized by a depigmented halo.
• Agminated nevus describes a cluster of melanocytic nevi in a localized area.
• Previous literature has not documented the co-occurrence of these two conditions.

Observation:

• Two pediatric cases presented with multiple halo nevi clustered in a specific body region.
• Clinical and histopathological examinations confirmed the diagnosis of agminated halo nevus.
• The central nevi exhibited varying degrees of regression, while the surrounding halos persisted.

Findings:

• This study introduces and describes 'agminated halo nevus' as a distinct clinical entity.
• Histopathology confirmed the benign nature of the melanocytic lesions.
• The findings suggest a potential variant presentation of halo nevi.

Implications:

• This report expands the understanding of melanocytic nevus variations.
• It provides a basis for future research into the etiology and behavior of agminated halo nevi.
• Clinicians should consider this entity in the differential diagnosis of clustered pigmented lesions with halos.