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A Randomized Controlled Trial of Mindfulness in Recovery from Colorectal Cancer.
Andrew McCombie1,2, Jennifer Jordan3,4, Roger Mulder3,4
1Te Whatu Ora (Health New Zealand) Waitaha Canterbury, Christchurch, 8011, New Zealand. Andrew.mccombie@cdhb.health.nz.
Mindfulness and active control groups both improved depression in colorectal cancer patients. Neither intervention was superior for psychological distress, and uptake was low.
Area of Science:
- Oncology
- Psychology
- Mindfulness-Based Interventions
Background:
- Colorectal cancer (CRC) patients often experience psychological distress.
- Mindfulness interventions are explored for managing distress in cancer patients.
Purpose of the Study:
- To compare a 4-week group mindfulness intervention against an active control (psychoeducation and cognitive behavioural skills) for reducing psychological distress in CRC patients.
Main Methods:
- Randomized controlled trial with 68 CRC patients allocated to mindfulness or active control groups.
- Interventions involved 2-h weekly sessions over 4 weeks.
- Outcomes measured at baseline, 8 weeks, and 6 months, including psychological distress (Hospital Anxiety and Depression Scale) and quality of life (QoL).
Main Results:
- Both groups showed reduced depression scores at 8 weeks.
- The active control group demonstrated greater improvement in generic mental QoL at 8 weeks.
- Mindfulness group reported reduced impotence symptoms, while the control group reported reduced faecal incontinence. Embarrassment symptoms increased less in the mindfulness group.
Conclusions:
- Mindfulness was not superior to the active control in reducing overall psychological distress.
- Both interventions led to some improvements in depression.
- Low patient uptake and high dropout rates were observed for both interventions.
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