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Updated: Aug 6, 2025

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry
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Focal segmental glomerulosclerosis with a mutation in the mitochondrially encoded NADH dehydrogenase 5 gene: A case

Tsukasa Naganuma1, Toshiyuki Imasawa2, Ikuo Nukui1

  • 1Division of Nephrology, Department of Internal Medicine, Yamanashi Prefectural Central Hospital, 1-1-1 Fujimi, Kofu, Yamanashi 400-0027, Japan.

Molecular Genetics and Metabolism Reports
|March 21, 2023
PubMed

Keywords:
ATP, adenosine triphosphateAiDIVs, age-inappropriately disarranged and irregularly sized vascular smooth muscle cellsCOX IV, cytochrome c oxidase subunit 4Case reportCr, creatinineFSGS, focal segmental glomerulosclerosisFocal segmental glomerulosclerosisGSECs, granular swollen epithelial cellsMELAS, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodesMRC, mitochondrial respiratory chainMT-ND5, mitochondrially encoded ND5Mitochondrial nephropathyNADH dehydrogenase 5ND5, NADH dehydrogenase 5OXPHOS:, oxidative phosphorylationPodocyteReCPos, red-coloured podocyteseGFR, estimated glomerular filtration ratemtDNA, mitochondrial DNAnDNA, nuclear DNAsCr, serum creatinine

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