MRI findings of primary intracranial sarcomas in children

Claudia Lazarte-Rantes1, Osmar Pillaca-Cruzado2, Nella Baca-Hinojosa3

  • 1Department of Diagnostic Imaging, Instituto Nacional de Salud del Niño San Borja, Av. Javier Prado Este 3101, 15037, Lima, Peru. clazarte@insnsb.gob.pe.

Pediatric Radiology
|March 21, 2023
PubMed

Insights

Primary intracranial sarcoma, a rare pediatric brain tumor, often shows contrast enhancement, diffusion restriction, and hemorrhage on MRI scans. These imaging features can help in diagnosis.

Area of Science:

  • Pediatric neuro-oncology
  • Neuroradiology
  • Oncologic imaging

Background:

  • Primary intracranial sarcoma is a rare, high-grade malignant brain tumor.
  • Limited data exists on pediatric primary intracranial sarcoma, especially regarding imaging characteristics.

Approach:

  • A cross-sectional descriptive observational study was conducted.
  • MRI characteristics of 18 pediatric patients (aged 1-18 years) diagnosed with primary intracranial sarcoma between 2015 and 2021 were reviewed.

Key Points:

  • 100% of cases showed contrast enhancement.
  • Diffusion restriction (78%), hemorrhage (89%), meningeal extension (67%), and necrosis (67%) were common findings.
  • The majority (72%) of tumors were supratentorial.

Conclusions:

  • Primary intracranial sarcomas are typically supratentorial.
  • MRI findings in pediatric primary intracranial sarcoma resemble those of other intracranial malignancies.
Abstract