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What Is a Preferred Retinal Locus?

Luminita Tarita-Nistor¹, Irina Sverdlichenko², Mark S Mandelcorn^3,4

¹Krembil Research Institute, Donald K Johnson Eye Institute, University Health Network, Toronto, Canada;

Annual Review of Vision Science

|March 21, 2023

Summary

This summary is machine-generated.

This review explores the preferred retinal locus (PRL) in macular disease patients, highlighting measurement challenges and development hypotheses. The study suggests current PRL definitions are incomplete, especially regarding binocular viewing, and calls for further research.

Keywords:

PRL binocular viewing central vision loss fixation stability macular degeneration preferred retinal locus

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Area of Science:

Ophthalmology
Neuroscience
Vision Science

Background:

Macular diseases significantly impact visual function.
The preferred retinal locus (PRL) is a key concept in understanding visual compensation in low vision.
Current understanding of PRL development and function remains incomplete.

Purpose of the Study:

To review the identification, measurement, and hypotheses of preferred retinal locus (PRL) development.
To assess the role of PRL as a reference point in the ocular motor system.
To discuss the functional and clinical implications of PRL in macular diseases.

Main Methods:

Literature review of studies on preferred retinal locus (PRL).
Analysis of monocular and binocular viewing conditions.
Examination of hypotheses regarding PRL development and its role in the ocular motor system.

Main Results:

Identification and measurement of PRL present significant challenges and pitfalls.
Several hypotheses exist regarding PRL development, but none are fully established.
The PRL's role as a stable reference point for the ocular motor system is under investigation.

Conclusions:

The current definition of preferred retinal locus (PRL) is likely incomplete.
Evaluating PRL within the context of binocular viewing is crucial.
Further research is needed to fully elucidate the nature and implications of PRL in macular diseases.