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Sequential Management of Macular Hole-Associated Rhegmatogenous Retinal Detachment: Case Report and Literature Review
Irina Sverdlichenko1, Safwan Tayeb1, Miguel Cruz Pimentel1
1Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Journal of Vitreoretinal Diseases
|November 20, 2025
Summary
This study presents a sequential surgical approach for macular hole-associated retinal detachment, combining pneumatic retinopexy and pars plana vitrectomy. This method successfully treated retinal detachment and closed macular holes in two patients.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Macular hole (MH)-associated retinal detachment is a complex condition requiring effective surgical strategies.
- Existing literature highlights various surgical techniques for MH-associated retinal detachment, with varying success rates.
Purpose of the Study:
- To present a novel sequential surgical approach for MH-associated retinal detachment.
- To evaluate the efficacy of preoperative pneumatic retinopexy followed by pars plana vitrectomy.
- To review and synthesize published literature on surgical management of this condition.
Main Methods:
- Retrospective chart review of two patients with MH-associated retinal detachment.
- Comprehensive literature search using PubMed for relevant studies.
- Analysis of surgical techniques, outcomes, and patient demographics.
Main Results:
- Two patients successfully treated with sequential pneumatic retinopexy and pars plana vitrectomy, achieving MH closure.
- Literature review of 502 cases: 65% female, 90% myopic.
- Overall MH closure rate of 64% and initial retinal reattachment rate of 95% across reviewed studies.
Conclusions:
- Sequential surgical approach effectively converts emergent retinal detachment into an elective MH repair.
- This strategy enhances the likelihood of successful macular hole closure.
- The described approach offers a promising alternative for managing MH-associated retinal detachment.

