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Related Concept Videos

Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

Factors Affecting Dissolution: Particle Size and Effective Surface Area

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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Nanoparticle: A Unique Strategy for Antifungal Agents.

Sudha Vishwakarma1, Geeta Bhagwat1

  • 1Department of Pharmaceutics, HK College of Pharmacy, Mumbai University, Mumbai, India.

Pharmaceutical Nanotechnology
|March 22, 2023
PubMed
Summary
This summary is machine-generated.

Nanotechnology offers innovative solutions for drug delivery, enhancing therapeutic compound transport and cellular translocation. This review explores advances in nanotechnology for antifungal treatments, aiming to improve drug viability and reduce toxicity.

Keywords:
Nanoparticleantifungal activitycarrierhealthcare industriesnanomaterialsnanoparticulate delivery

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Pharmacology

Background:

  • Nanomaterials offer advanced capabilities for therapeutic compound delivery.
  • Nanoparticles serve as significant drug carriers in the healthcare industry.
  • Biologically active compounds benefit from the adaptable qualities of nanomaterials.

Approach:

  • This review provides an overview of recent advancements in nanotechnology for antifungal treatment.
  • It examines the development of various nanoparticles as drug delivery systems.
  • The focus is on overcoming challenges associated with conventional antifungal agents.

Key Points:

  • Nanoparticles enhance drug delivery by improving transport and cellular translocation.
  • Nanoparticulate systems are designed to reduce toxicity and dosing frequency.
  • These systems aim to increase the overall viability and efficacy of therapeutic drugs.

Conclusions:

  • Nanotechnology presents a promising avenue for developing effective antifungal therapies.
  • The review highlights the potential of nanomaterials to overcome limitations of current antifungal agents.
  • Further research in this area could lead to improved patient outcomes in treating fungal infections.