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Cecal malakoplakia: A case report

Jin Woon Jeong1, Ji Hyun Noh1, Jeong Hyun Kang1

  • 1Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Korean Journal of Clinical Oncology
|March 22, 2023
PubMed

Insights

This study reports a rare case of cecal malakoplakia in a patient undergoing follow-up for cervical cancer. The findings highlight the importance of monitoring immunosuppressed patients for rare conditions like malakoplakia.

Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Malakoplakia is a rare chronic granulomatous disease typically affecting the genitourinary tract.
  • It is often associated with immunosuppression and infectious processes.
  • Cervical cancer treatment, including surgery and chemotherapy, can lead to immunosuppression.

Observation:

  • A 74-year-old female, treated for cervical cancer, presented with an infiltrative mass near the cecum during a 1-year follow-up.
  • Computed tomography revealed a 6 cm mass between the cecal base and the right psoas muscle.
  • An ileocectomy was performed for diagnostic purposes.

Findings:

  • Histopathologic examination confirmed the diagnosis of cecal malakoplakia.
  • This represents a rare occurrence of malakoplakia in the cecum, particularly in the context of post-cervical cancer treatment.

Implications:

  • The case underscores the association between immunosuppression, such as that induced by chemotherapy, and the development of malakoplakia.
  • Close observation is recommended for immunosuppressed patients to detect rare conditions like cecal malakoplakia early.
  • This case contributes to the understanding of extragenitourinary manifestations of malakoplakia.
Keywords:
MalakoplakiaUterine cervical neoplasms

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