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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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Disseminated Intravascular Coagulation Post Endovascular Aortic Repair
Nikolaos Schizas1, Georgia Nazou2, Constantine Antonopoulos3
1Department of Cardiac Surgery, Medical School, National and Kapodistrian University of Athens, Greece.
Vascular and Endovascular Surgery
|March 22, 2023
Summary
Disseminated Intravascular Coagulation (DIC) following Endovascular Aneurysm Repair (EVAR) is rare but serious. Prompt diagnosis and endoleak treatment are crucial for managing this potentially lethal condition.
Area of Science:
- Vascular Surgery
- Hematology
- Critical Care Medicine
Background:
- Disseminated Intravascular Coagulation (DIC) post-EVAR is an exceptionally rare complication.
- Limited case reports exist, making management strategies unclear.
Purpose of the Study:
- To comprehensively review and analyze all available data on DIC occurring after EVAR.
- To synthesize existing evidence for a better understanding of this rare complication.
Main Methods:
- Systematic literature search across major databases for studies on DIC post-EVAR.
- Analysis of clinical parameters, predisposing factors, mortality, and morbidity.
- Review of 15 publications detailing 17 patient cases.
Main Results:
- Endoleak was identified as the primary cause in 71% of cases.
- Mortality rate for DIC post-EVAR was 29%, irrespective of treatment.
- Effective treatment was achieved in 47% of patients, with improved outcomes from conservative or endovascular interventions.
Conclusions:
- DIC after EVAR, though infrequent, is a life-threatening condition requiring immediate diagnosis and management.
- Addressing endoleak is key to normalizing coagulation parameters and improving patient outcomes.
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