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Translating from mouse to man to better understand immune-mediated inflammatory diseases
Dominik Aschenbrenner1, Richard M Siegel1
1Immunology Disease Area and Translational Medicine, Novartis Institutes of BioMedical Research, Basel, Switzerland.
Cell Reports. Medicine
|March 22, 2023
Abstract:
Lilja et al.1 explore single-cell transcriptomes across multiple organs of mice with collagen-induced arthritis. They apply network analysis to prioritize functional pathways that support or suppress inflammation and integrate findings with tissue transcriptomics in human immune-mediated inflammatory diseases.

