Geriatric Pharmacotherapy Case Series: Potential Drug Interactions With Antiplatelet Medications and Cannabidiol-A

Stephen A Brown1, Katie Boyd1, Angela R Thomason1

  • 1McWhorter School of Pharmacy, Samford University, Birmingham, Alabama.

Insights

Patients using clopidogrel should avoid cannabidiol (CBD) due to potential drug interactions. CBD use with P2Y12 inhibitors may increase cardiovascular and bleeding risks, necessitating informed patient and provider awareness.

Area of Science:

  • Pharmacology
  • Cardiology
  • Geriatrics

Background:

  • A 76-year-old male with hypertension and prior stroke experienced an acute myocardial infarction.
  • The patient was on clopidogrel and aspirin for secondary stroke prevention.
  • He reported prior use of cannabidiol (CBD) oil for knee pain and wished to continue it during rehabilitation.

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