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Trichofolliculoma: A Case Series
Baklouti Massara1, Khadija Sellami1, Soumaya Graja2
1Drs. Massara, Khadija, Sana, Fatma, Emna, and Hamida are with the Dermatology Department at Hedi Chaker Hospital at the University of Sfax in Sfax, Tunisia.
The Journal of Clinical and Aesthetic Dermatology
|March 23, 2023
Summary
Trichofolliculoma (TF) is a rare benign tumor. Histopathological examination is crucial for diagnosis, as clinical presentation can be misleading, especially regarding central tufted hairs.
Area of Science:
- Dermatology
- Pathology
- Oncology
Background:
- Trichofolliculoma (TF) is a rare benign adnexal tumor with follicular differentiation.
- It typically presents as an isolated nodule on the face or scalp, often with protruding central hairs.
Observation:
- A retrospective series of eleven histologically confirmed TF cases was analyzed.
- The mean age at excision was 46 years, with a female predominance (M/F ratio 0.37).
- Lesions were predominantly facial (63.6%), presenting as papules or nodules (average 6.7mm), sometimes with a central pit (54%).
Findings:
- Histologically, all cases showed a dilated hair follicle with keratinous material and branched follicular structures.
- Central tufted hairs were observed in a minority of cases, corresponding to multiple secondary vellus hair follicles.
- TF predominantly affects women without significant age predilection and is often located on the face.
Implications:
- Histopathological examination is the gold standard for diagnosing TF, as clinical presentation can be variable and challenging.
- Dermoscopic findings may differ based on lesion age.
- Further case series are needed to fully understand TF characteristics.
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