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Detection of Infectious Virus from Field-collected Mosquitoes by Vero Cell Culture Assay
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Powassan Virus Infection Detected by Metagenomic Next-Generation Sequencing, Ohio, USA
Emerging Infectious Diseases
|March 23, 2023
Abstract:
We describe a 4-year-old male patient in Ohio, USA, who had encephalitis caused by Powassan virus lineage 2. Virus was detected by using metagenomic next-generation sequencing and confirmed with IgM and plaque reduction neutralization assays. Clinicians should recognize changing epidemiology of tickborne viruses to enhance encephalitis diagnosis and management.
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