Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammation01:38

Inflammation

54.2K
Overview
54.2K
Inflammatory Response01:28

Inflammatory Response

3.2K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
3.2K
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

14
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
14
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

62
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
62
Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

11.7K
The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
11.7K
Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

3.0K
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic challenges of Paederus dermatitis: a case series in military personnel.

Medicina clinica·2026
Same author

Stroke and systemic embolism following atrial fibrillation ablation: the EMBOL-AF Global Registry.

European heart journal·2026
Same author

Artificial intelligence-enabled electrocardiography to predict impending episodes of ventricular tachycardia in individuals under continuous heart rhythm monitoring.

The Cochrane database of systematic reviews·2026
Same author

ECG-XPLAIM: eXPlainable Locally-adaptive Artificial Intelligence Model for arrhythmia detection from large-scale electrocardiogram data.

Frontiers in cardiovascular medicine·2025
Same author

Major arrhythmias in non-dilated left ventricular cardiomyopathy: a novel prediction score.

European heart journal·2025
Same author

Commentary on ventricular arrhythmias in acute heart failure: Critical insights into the 2024 ACVC-EHRA- HFA consensus statement.

International journal of cardiology·2025

Related Experiment Video

Updated: Aug 5, 2025

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.6K

Immunity and inflammation in cardiovascular disorders.

Vennela Boyalla1, Enrique Gallego-Colon2, Michael Spartalis3

  • 1University of Manchester, Manchester, UK.

BMC Cardiovascular Disorders
|March 24, 2023
PubMed
Summary

The immune system and inflammation significantly impact cardiovascular disease (CVD). Further research is needed to fully understand these roles for better risk assessment and treatments.

Keywords:
CardiovascularImmunityInflammationMolecularPathophysiology

More Related Videos

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
05:51

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

13.2K
On-Chip Endothelial Inflammatory Phenotyping
12:43

On-Chip Endothelial Inflammatory Phenotyping

Published on: July 21, 2012

11.0K

Related Experiment Videos

Last Updated: Aug 5, 2025

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

6.6K
A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
05:51

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology

Published on: May 6, 2014

13.2K
On-Chip Endothelial Inflammatory Phenotyping
12:43

On-Chip Endothelial Inflammatory Phenotyping

Published on: July 21, 2012

11.0K

Area of Science:

  • Immunology
  • Inflammation Research
  • Cardiovascular Medicine

Background:

  • Recent advancements have enhanced the understanding of immune system involvement in cardiovascular disease (CVD).
  • Inflammation is increasingly recognized as a critical factor in the development and progression of CVD.
  • Existing knowledge gaps necessitate further investigation into the complex interplay between immunity and cardiovascular health.

Discussion:

  • The Collection aims to consolidate current research on immunity and inflammation in CVD.
  • It seeks to bridge knowledge gaps and foster new therapeutic strategies.
  • Understanding these biological mechanisms is crucial for improving patient outcomes.

Key Insights:

  • Immune responses and inflammatory processes are integral to cardiovascular pathophysiology.
  • Novel biomarkers and therapeutic targets are emerging from this research area.
  • Interdisciplinary approaches are vital for advancing CVD management.

Outlook:

  • Future research will likely focus on personalized medicine approaches targeting specific immune pathways in CVD.
  • The findings are expected to lead to improved diagnostic tools and treatment protocols.
  • This Collection will serve as a valuable resource for researchers and clinicians in the field.