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Published on: January 18, 2018
Same day discharge versus overnight observation following chronic total occlusion percutaneous coronary intervention:
Bahadir Simsek1, Jaikirshan Khatri2, Laura Young2
1Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Insights
Same day discharge (SDD) after chronic total occlusion (CTO) percutaneous coronary intervention (PCI) is increasingly feasible, with radial-only access strongly associated with SDD. This approach is safe for select patients, showing low readmission rates.
Area of Science:
- Cardiology
- Interventional Cardiology
- Health Services Research
Background:
- Same day discharge (SDD) following chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has been understudied.
- The Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO) database provides insights into this practice.
Purpose of the Study:
- To evaluate the clinical, angiographic, and procedural characteristics of patients undergoing CTO PCI with same day discharge versus overnight observation.
- To identify factors associated with SDD after CTO PCI.
Main Methods:
- Analysis of 7181 patients from the PROGRESS-CTO registry who underwent CTO PCI.
- Comparison of patient characteristics, procedural success, and adverse events between SDD and overnight observation groups.
- Multivariable logistic regression to identify predictors of SDD and overnight observation.
Main Results:
- The SDD rate increased from 3% in 2015 to 21% in 2022, with 13% of patients discharged same day.
- Patients undergoing SDD were less likely to have comorbidities like heart failure, chronic lung disease, or anemia.
- Technical success was similar between groups, but in-hospital major adverse cardiovascular events were lower in the SDD group (0.0% vs. 0.4%).
- Radial-only access was the strongest predictor of SDD (OR: 2.45), while prior myocardial infarction and chronic lung disease were associated with overnight observation.
Conclusions:
- Same day discharge is feasible and increasingly utilized for select patients after CTO PCI.
- Radial-only access is a key factor facilitating SDD in CTO PCI.
- The study demonstrates a growing trend and safety profile for SDD in this patient population.
Background:
Same day discharge (SDD) following chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.
Methods:
We evaluated the clinical, angiographic, and procedural characteristics of patients discharged the same day versus those kept for overnight observation in the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO, NCT02061436).
Results:
Of the 7181 patients who underwent CTO PCI, 943 (13%) had SDD. The SDD rate increased from 3% in 2015 to 21% in 2022. Patients with SDD were less likely to have a history of heart failure (21% vs. 26%, p = 0.005), chronic lung disease (10% vs. 15%, p = 0.001), or anemia (12% vs. 19%, p < 0.001). Technical success (87% vs. 88%, p = 0.289) was similar, but in-hospital major adverse cardiovascular events (0.0% vs. 0.4%, p = 0.041) were lower in SDD. In multivariable logistic regression analysis, prior myocardial infarction odds ratio (OR): 0.71 (95% confidence interval [CI]: 0.59-0.87, p = 0.001), chronic lung disease OR: 0.64 (95% CI: 0.47-0.88, p = 0.006), and increasing procedure time OR: 0.93 (95% CI: 0.91-0.95, p < 0.001, per 10-min increase) were associated with overnight observation, while radial-only access OR: 2.45 (95% CI: 2.03-2.96, p < 0.001) had the strongest association with SDD. In the SDD, 2 (0.4%) of 514 patients were readmitted, due to retroperitoneal bleeding (n = 1) and ischemic stroke (n = 1).
Conclusion:
The overall frequency of SDD after CTO PCI was 13% and has been increasing over time. SDD is feasible in select patients following CTO PCI, and radial-only access had the strongest association with SDD.
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