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Updated: Aug 5, 2025

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
3D printing personalized guide plate in the management of recurrent intramuscular venous malformations: A single
Tao Han1, Shupei Jiang1, Jiageng Xiong1
1Department of Burns and Plastic Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Objective:
This study aimed to investigate the feasibility and effectiveness of 3D printing personalized guide plate in the management of recurrent intramuscular venous malformations (IVM).
Methods:
Fifteen patients with recurrent IVM were retrospectively assessed. 3D-slicer software was used to extract and reconstruct the imaging data from CT and/or MRI to highlight the morphology, size, and puncture depth of the lesion. With the guidance of personalized plate, complete excision of the IVM was adopted along the pre-marked (methylene blue, MB) margin.
Results:
Personalized guide plate matched involved extremity well, and MB-puncture approach was consistent with preoperative design. All IVMs were removed radically in one single session. Complete pain relief was obtained in all cases postoperatively.
Conclusion:
The application of 3D printing guide plate can be safe, effective, and reliable to confirming the precise margin of IVM, renders a promising technique with a high practical value in resection of recurrent lesion.

