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Ten future challenges for synthetic biology.

Olivia Gallup1, Hia Ming1, Tom Ellis1,2

  • 1Department of Bioengineering Imperial College London London UK.

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|March 27, 2023
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Summary
This summary is machine-generated.

Synthetic biology is a mature field driving innovation. Future research will focus on creating synthetic life, custom genomes, and advanced engineering methods like AI and evolution control.

Keywords:
artificial lifeautomationbiosensorsbiotechnologybio‐economygenome engineeringgenomicsindustrylearning (artificial intelligence)microbial engineeringreviewssustainable developmentsynthetic biology

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Area of Science:

  • Synthetic Biology
  • Biotechnology
  • Bioeconomy

Background:

  • Synthetic biology has matured over two decades, significantly impacting the bioeconomy, biomedical sciences, and biotechnology.
  • The field is poised for further advancements, necessitating a forward-looking perspective on its evolution.

Purpose of the Study:

  • To identify and discuss ten key technological advances expected in the next generation of synthetic biology research and investment.
  • To inspire new entrants to the field and outline potential future directions for synthetic biology over the coming decades.

Main Methods:

  • Discussion of ambitious projects including synthetic life creation, cell simulators, and custom genome design.
  • Exploration of novel biological engineering methods leveraging automation, deep learning, and controlled evolution.

Main Results:

  • Identification of ten anticipated technological advancements in synthetic biology.
  • A forward-looking perspective on the field's potential evolution and innovation.

Conclusions:

  • Synthetic biology is a dynamic and rapidly advancing field with significant future potential.
  • Continued research and investment in areas like synthetic life, AI-driven engineering, and genome customization will shape the future of biotechnology.