Related Experiment Video
Updated: Aug 5, 2025

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
Published on: February 23, 2020
Determining the filtration effectiveness of non-standard respiratory protective devices by an ad-hoc laboratory
Mauro Scungio1, Giulia Parlani1
1Department of Economics, Engineering, Society and Business Organization (DEIM). University of Tuscia, Via Del Paradiso 47, Viterbo, Italy.
Abstract:
The recent pandemic caused by COVID-19 profoundly changed people's habits. Wearing a face mask has become usual in everyday life to reduce the risk of infection from airborne diseases. At the beginning of the pandemic, the massive request of surgical or filtering face piece (FFP) masks resulted in a global shortage of these devices for the most exposed people, such as healthcare workers. Due to this high demand for respiratory protective devices, many industrial plants have partly converted to the production of face masks using adapted materials and not complying with any specific regulation (non-standard respiratory protective devices or community masks). In this work, an ad-hoc laboratory methodology has been developed to evaluate the filtration efficiency of the materials that compose the community masks using specific instrumentation. The instrumentation consists of three main tools: an aerosol generator, a specifically designed measuring chamber, and an optical particle sizer (OPS) for the measurement of aerosol concentration. The generated aerosol was sent into the measuring chamber, divided into two separate sections by the respiratory mask. The OPS measured the aerosol mass concentration upstream and downstream of the respiratory mask, and from the concentration difference the filtration efficiency was evaluated. The proposed methodology has been validated by evaluating the particle filtration efficiency (PFE) of certified respiratory masks and was then applied for the evaluation of the filtration efficiency of different types of non-standard or community masks to analyze their effectiveness in protecting from the risk of infection of airborne diseases.

