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Natural-product-based fluorescent probes: recent advances and applications
Dan-Bi Sung1, Jong Seok Lee1,2
1Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology Busan Republic of Korea jslee@kiost.ac.kr.
RSC Medicinal Chemistry
|March 27, 2023
Summary
Natural products are revolutionizing fluorescent probes for biology and medicine. This review highlights recent advances in natural-product-based probes for bioimaging and biochemical studies.
Area of Science:
- Biochemistry and Molecular Biology
- Chemical Biology
- Biomedical Imaging
Background:
- Fluorescent probes are versatile tools in biology, drug discovery, diagnostics, and environmental monitoring.
- They enable non-invasive detection of biological substances, detailed cell imaging, tracking of in vivo reactions, and disease biomarker monitoring.
- Natural products have emerged as promising recognition units for developing advanced fluorescent probes due to extensive research interest.
Purpose of the Study:
- To review representative natural-product-based fluorescent probes.
- To highlight recent discoveries in this field.
- To focus on applications in fluorescent bioimaging and biochemical studies.
Main Methods:
- Literature review of natural-product-based fluorescent probes.
- Analysis of recent discoveries and applications.
- Focus on studies utilizing these probes for bioimaging and biochemical analysis.
Main Results:
- Identification of various natural products as effective recognition units for fluorescent probes.
- Demonstration of the utility of these probes in diverse bioimaging applications.
- Showcasing their role in biochemical studies and disease biomarker detection.
Conclusions:
- Natural-product-based fluorescent probes offer significant advantages for biological and medical research.
- These probes are valuable for advanced bioimaging and biochemical investigations.
- Continued exploration of natural products will likely yield novel and improved fluorescent probe technologies.
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