Related Experiment Video
Updated: Aug 5, 2025
03:26
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
2.1K
Age-related white matter hyperintensities and overactive bladder: A systematic review
Ricardo Pereira E Silva1,2, Diana Aguiar Sousa2,3, Filipe Abadesso Lopes1
1Serviço de Urologia, Centro Hospitalar Universitário Lisboa Norte, Lisboa, Portugal.
Neurourology and Urodynamics
|March 27, 2023
Summary
Age-related white matter hyperintensities (ARWMH) are linked to overactive bladder (OAB) symptoms. Moderate to severe ARWMH increases the likelihood of OAB and urgency urinary incontinence in older adults.
Area of Science:
- Neurology
- Urology
- Geriatrics
Background:
- Age-related white matter hyperintensities (ARWMH) are common findings on brain MRI in older adults.
- ARWMH have been anecdotally linked to lower urinary tract symptoms/dysfunction (LUTS/LUTD), including overactive bladder (OAB).
Conclusions:
- High-quality evidence linking ARWMH and OAB remains scarce.
- Patients with moderate-to-severe ARWMH exhibit increased OAB symptoms, particularly UUI.
- Standardized assessment tools for both ARWMH and OAB are recommended for future research.
Related Concept Videos
01:23Urinary Bladder
1.1K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
1.1K
01:21Nursing Assessment of the Genitourinary System I: Health History
53
The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
53
01:19Urodynamic Studies: Uroflowmetry
200
Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
200
01:26The Micturition Reflex
809
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
809
01:19Anatomy of the Genitourinary System II: Bladder and Urethra
155
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
155
01:22Imaging Studies VI: Voiding Cystourethrography and Cystography
59
Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
59