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Studies directed toward introduction of N6-isopentenyladenosine and its 2-methylthio analogue into
P Swiderski1, P Dembek, W S Antkowiak
1Faculty of Chemistry, Adam Mickiewicz University, Poznań, Poland.
Nucleic Acids Symposium Series
|January 1, 1987
Abstract:
A new efficient route of i6A and ms2i6A synthesis, especially useful for the preparation of i6A-containing oligoribonucleotides eg. Api6A has been proposed. The method is based on aminolysis of a 6-methylsulfonylpurine system formed by oxidation of its 6-methylthio precursor.