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Synthesis and cloning of a human beta-casomorphin-5 gene
S Hoffmann1, E Günther, G Kunze
1Martin Luther University, Department of Chemistry, Halle/S, GDR.
Nucleic Acids Symposium Series
|January 1, 1987
Abstract:
As so far a singularity among opioid peptides, bovine beta-casomorphin-5 has been shown to display pronounced cardiatic activities. The gene sequence of a human beta-casomorphin-5, including plasmid insertion and fusion protein expression and cleavage instrumentary, has been synthesized by a manual phosphoramidite procedure and cloned in a bacterial system.