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A solution to the problem of 3'----2'-O-phosphoryl migration in oligoribonucleotide synthesis
H Tanimura1, T Fukazawa, M Sekine
1Department of Life Chemistry, Tokyo Institute of Technology, Yokohama, Japan.
Nucleic Acids Symposium Series
|January 1, 1987
Abstract:
Oligoribonucleotides were obtained without contamination of 2'-5' linked regioisomers by means of polymer support when Thp group was employed as 2'-hydroxyl protecting group.