Predicting childhood overweight status by accelerated weight gain from neonatal period to infancy

Shahin Koohmanaee1, Hamidreza Badeli1, Afagh Hassanzadeh Rad1

  • 1Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

Insights

Accelerated weight gain in infancy, particularly by 18 months, can predict childhood obesity. Early identification of rapid weight gain (RWG) is crucial for public health interventions.

Area of Science:

  • Pediatrics
  • Public Health
  • Childhood Obesity Research

Background:

  • Childhood obesity is a growing public health concern.
  • Obesity in early life can lead to long-term health issues, including cardiovascular problems and adult obesity.
  • Infant weight gain patterns are being investigated as early indicators of future overweight status.

Purpose of the Study:

  • To assess the relationship between accelerated weight gain during infancy and overweight status in 7-year-old children.
  • To identify optimal time points and thresholds for rapid weight gain (RWG) that predict later childhood obesity.

Main Methods:

  • A historical cohort study involving 637 7-year-old students in Guilan, Iran.
  • Collected demographic data and infant weight at 4, 6, 12, and 18 months.
  • Utilized ROC curve analysis to determine the best cutoff points for RWG predicting 7-year-old obesity based on sensitivity and specificity.

Main Results:

  • The study analyzed rapid weight gain (RWG) across different infant periods (0-4, 0-6, 0-12, 0-18 months).
  • The highest predictive power for obesity at age 7 was observed for RWG between 0-18 months (AUC=0.7 ± 0.05).
  • A RWG of 8.55 kg by 18 months showed 65.5% sensitivity and 72.0% specificity for predicting childhood obesity.

Conclusions:

  • Findings suggest that rapid weight gain in infancy, especially up to 18 months, is a significant predictor of childhood obesity.
  • Earlier monitoring of infant weight gain is recommended, potentially even before 3 years of age.
  • This research highlights the importance of early intervention strategies targeting infant weight management.
Abstract

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