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Titanium Lattice Structures Produced via Additive Manufacturing for a Bone Scaffold: A Review
Fabio Distefano1, Salvatore Pasta2,3, Gabriella Epasto1
1Department of Engineering, University of Messina, C.da Di Dio, 98166 Messina, Italy.
Journal of Functional Biomaterials
|March 28, 2023
Summary
Additive manufacturing enables Ti6Al4V porous scaffolds for bone defects. This review details mechanical and morphological needs for osteointegration, guiding scaffold design for better bone repair.
Area of Science:
- Biomedical Engineering
- Materials Science
- Orthopedic Surgery
Background:
- Additive manufacturing advances scaffold fabrication for bone substitutes.
- Ti6Al4V alloy is favored for bone implants due to its biological and mechanical properties.
- Regenerating critical bone defects remains a significant clinical challenge.
Purpose of the Study:
- To review the last decade's findings on Ti6Al4V porous scaffolds.
- To summarize mechanical and morphological requirements for osteointegration.
- To evaluate scaffold suitability for biomedical applications.
Main Methods:
- Literature review of Ti6Al4V porous scaffolds (last 10 years).
- Analysis of pore size, surface roughness, and elastic modulus effects.
- Application of the Gibson-Ashby model for mechanical comparison.
Main Results:
- Identified key mechanical and morphological factors influencing osteointegration.
- Pore size, surface roughness, and elastic modulus significantly impact scaffold performance.
- Lattice material mechanical performance was compared to human bone using the Gibson-Ashby model.
Conclusions:
- Ti6Al4V porous scaffolds show promise for bone defect repair.
- Optimizing pore size, surface roughness, and elastic modulus is crucial for osteointegration.
- The Gibson-Ashby model aids in assessing scaffold suitability for bone regeneration.
