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A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
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Small bowel obstruction: what a gastroenterologist needs to know.
Foong Way David Tai1,2, Reena Sidhu1,2
1Academic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals.
Current Opinion in Gastroenterology
|March 28, 2023
Summary
Small bowel diseases causing obstruction are challenging to diagnose and treat. Advanced imaging, endoscopic balloon dilatation, and biologic therapy can help manage these conditions and potentially delay surgery.
Area of Science:
- Gastroenterology
- Surgical Gastroenterology
Background:
- Intra-abdominal adhesions and intestinal hernias are primary causes of small bowel obstruction.
- Small bowel diseases are less common causes of obstruction but present diagnostic and therapeutic challenges.
Approach:
- Review focuses on small bowel diseases predisposing to obstruction, detailing diagnostic and treatment challenges.
- Utilizes computed tomography (CT) and magnetic resonance (MR) enterography for improved diagnosis of partial small bowel obstruction.
Key Points:
- Endoscopic balloon dilatation can delay surgery for short, accessible fibrostenotic Crohn's strictures and NSAID diaphragm disease.
- Biologic therapy may decrease surgical necessity in inflammatory small bowel Crohn's disease.
- Surgery is reserved for refractory chronic radiation enteropathy causing obstruction or nutritional issues.
Conclusions:
- Small bowel diseases causing obstruction are difficult to diagnose, often requiring extensive investigations and surgery.
- Biologics and endoscopic balloon dilatation offer options to delay or prevent surgical intervention in select cases.
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