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Vitamins and Radioprotective Effect: A Review
Inés Lledó1, Blanca Ibáñez1, Ana Melero2
1Food & Health Lab, Institute of Materials Science, University of Valencia, 46980 Paterna, Spain.
Antioxidants (Basel, Switzerland)
|March 29, 2023
Summary
Vitamins A, C, D, and E show radioprotective properties, reducing radiation
Area of Science:
- Nutritional Science
- Radiation Biology
- Biochemistry
Background:
- Radiation exposure poses risks to biological systems.
- Vitamins are essential micronutrients with potential protective roles.
- Understanding the radioprotective effects of vitamins is crucial for mitigating radiation damage.
Purpose of the Study:
- To review and synthesize evidence on the radioprotective effects of vitamins.
- To identify specific vitamins demonstrating radioprotective properties.
- To assess vitamin efficacy across ex vivo, in vitro, and in vivo models.
Main Methods:
- Systematic literature review adhering to the PRISMA statement.
- Searches conducted in PubMed and Embase databases.
- Inclusion of 38 relevant articles detailing vitamin radioprotection studies.
Main Results:
- Vitamins A, C, D, and E exhibited radioprotective effects.
- Vitamin E demonstrated the most significant radioprotective properties.
- Vitamins C, A, and D also showed notable protective effects.
- Vitamins were used in various forms, including natural, supplemented, and in combination with other compounds.
Conclusions:
- Certain vitamins, particularly A, C, D, and E, possess significant radioprotective capabilities.
- Vitamin supplementation or intake in natural form may help reduce radiation-induced damage.
- Further research may explore optimal formulations and applications of these vitamins for radiation protection.
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