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Risk of Acute Myocardial Infarction in Pneumoconiosis: Results from a Retrospective Cohort Study
Ju-Hsin Chang1,2, Te-Chun Shen3,4,5, Ke-Wei Chen1,6
1Graduate Institute of Clinical Medicine Science, China Medical University, No. 91, Xue-Shi Road, Taichung 404, Taiwan.
Biomedicines
|March 29, 2023
Summary
Pneumoconiosis (PCN) patients face a higher risk of acute myocardial infarction (AMI). This study found PCN is linked to increased AMI incidence, highlighting the need for preventative care in these individuals.
Area of Science:
- Cardiology
- Occupational Medicine
- Public Health
Background:
- Pneumoconiosis (PCN) is associated with pulmonary and cardiovascular comorbidities.
- The specific relationship between PCN and acute myocardial infarction (AMI) requires further investigation.
Purpose of the Study:
- To clarify the association between PCN and the subsequent risk of AMI.
- To investigate the impact of PCN on AMI risk using a population-based retrospective cohort study.
Main Methods:
- Utilized Taiwan's National Health Insurance Database for a retrospective cohort study (2008-2018).
- Included 7556 patients with PCN and 7556 matched controls without PCN.
- Employed propensity score matching and Cox proportional hazard regression to assess AMI risk until 2019.
Main Results:
- Patients with PCN exhibited a 1.34-fold higher incidence of AMI compared to controls (4.33 vs. 3.23 per 1000 person-years).
- The adjusted hazard ratio (aHR) for AMI in PCN patients was 1.36 (95% CI: 1.08-1.72).
- Increased emergency department visits among PCN patients correlated with higher AMI risk (aHR: 1.30 for <1 visit, aHR: 1.68 for ≥1 visit).
Conclusions:
- Pneumoconiosis is significantly associated with an elevated risk of developing acute myocardial infarction.
- Healthcare providers should prioritize AMI prevention strategies for patients diagnosed with PCN.
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