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Updated: Aug 5, 2025

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Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
Published on: March 3, 2023
489
Laparoscopic Microwave Ablation: Which Technologies Improve the Results
Roberto Santambrogio1, Maurizio Vertemati2, Matteo Barabino3
1UOC di Chirurgia Generale, Ospedale Fatebenefratelli, ASST Fatebenefratelli Sacco, 20121 Milano, Italy.
Cancers
|March 29, 2023
Summary
Laparoscopic thermoablation offers an alternative for hepatocellular carcinoma (HCC) when surgery isn't possible. Advanced imaging like 3D modeling and ICG fluorescence enhances surgical precision for better HCC treatment outcomes.
Area of Science:
- Hepatobiliary Surgery
- Minimally Invasive Oncology
- Medical Imaging Technologies
Background:
- Hepatocellular carcinoma (HCC) often precludes liver resection, necessitating alternative treatments.
- Percutaneous thermoablation is an option for inoperable HCC, but not always feasible due to lesion visibility or location.
- Laparoscopic thermoablation is indicated when percutaneous approaches fail, yet intraoperative 3D navigation remains challenging.
Purpose of the Study:
- To explore advanced technologies for improving laparoscopic thermoablation precision in HCC treatment.
- To detail the integration of 3D hepatic modeling, ICG fluorescence, and laparoscopic ultrasound for enhanced surgical planning.
- To demonstrate how these tools facilitate a personalized laparoscopic approach for HCC patients.
Main Methods:
- Utilizing 3D reconstruction of CT/MRI scans for virtual and augmented reality surgical guidance.
- Employing indocyanine green (ICG) fluorescence imaging to delineate tumor margins during laparoscopy.
- Integrating laparoscopic ultrasound with contrast media for improved lesion localization and characterization.
Main Results:
- 3D hepatic modeling aids in precise preoperative surgical planning and intraoperative visualization.
- ICG fluorescence imaging enhances the accuracy of laparoscopic thermoablation.
- Laparoscopic ultrasound with contrast improves the identification and assessment of HCC lesions.
Conclusions:
- Hepatic 3D modeling, ICG fluorescence, and laparoscopic ultrasound are valuable tools for HCC treatment.
- These technologies significantly improve preoperative surgical preparation and enable personalized laparoscopic approaches.
- The combined use of these modalities enhances precision and potentially improves outcomes for laparoscopic thermoablation in HCC.

