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Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the

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Cardiovascular risk factors like high glucose and blood pressure are common in older adults. This study reveals insights into their control and kidney function in the 70+ population.

Keywords:
HbA1cLDL-cholesterolblood pressureelderly populationestimated glomerular filtration rateurine albumin to creatinine ratio

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Area of Science:

  • Gerontology
  • Cardiology
  • Nephrology

Background:

  • Cardiovascular risk factors are prevalent in the elderly.
  • Limited population-based data exists on cardiovascular risk factor control in this demographic.
  • The AugUR cohort provides a valuable dataset for studying individuals aged 70+.

Purpose of the Study:

  • To assess the prevalence of uncontrolled cardiovascular risk factors in the 70+ population.
  • To investigate the association between these risk factors and kidney function (eGFR, UACR).
  • To provide insights into cardiovascular risk factor management in older adults.

Main Methods:

  • Cross-sectional analysis of the AugUR cohort (n=2215).
  • Assessment of LDL-cholesterol, HbA1c, and blood pressure levels.
  • Evaluation of associations with estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR).

Main Results:

  • 76.1% had high LDL-cholesterol; 6.3% had high HbA1c; 6.8% had high systolic blood pressure; 26.5% had low systolic blood pressure.
  • High HbA1c linked to impaired kidney function in untreated individuals.
  • High blood pressure associated with increased UACR; low blood pressure associated with impaired eGFR in diuretic users.

Conclusions:

  • Significant prevalence of uncontrolled cardiovascular risk factors in individuals aged 70-95.
  • Specific associations found between blood pressure, HbA1c, and kidney function markers.
  • Highlights the need for better cardiovascular risk management strategies in the elderly population.