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A guide to appropriately planning and conducting meta-analyses: part 2-effect size estimation, heterogeneity and
Kyle N Kunze1, Jeffrey Kay2, Ayoosh Pareek3
1Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA. kylekunze7@gmail.comm.
Abstract:
Meta-analyses by definition are a subtype of systematic review intended to quantitatively assess the strength of evidence present on an intervention or treatment. Such analyses may use individual-level data or aggregate data to produce a point estimate of an effect, also known as the combined effect, and measure precision of the calculated estimate. The current article will review several important considerations during the analytic phase of a meta-analysis, including selection of effect estimators, heterogeneity and various sub-types of meta-analytic approaches.
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