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Updated: Aug 5, 2025

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
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[Development of demetia therapeutics regurating synaptic plasticity]

Kohji Fukunaga1,2

  • 1BRI Pharma Incorporated.

Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica
|March 29, 2023
PubMed
Summary

A novel therapeutic candidate, SAK3, shows promise for Alzheimer's disease (AD) by enhancing neuronal plasticity and activating proteasome activity. This approach may reverse cognitive decline and reduce amyloid-beta plaque deposition in AD patients.

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