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Updated: Aug 5, 2025

Bioprintable Alginate/Gelatin Hydrogel 3D In Vitro Model Systems Induce Cell Spheroid Formation
Published on: July 2, 2018
2.5D printing of a yield-stress fluid
Simon Colanges1,2, Jean-Noël Tourvieille1,3, Pierre Lidon1
1Univ. Bordeaux, Laboratory of the Future, CNRS, Solvay, 33600, Pessac, France.
Abstract:
We report on direct ink writing of a model yield-stress fluid and focus on the printability of the first layer, the one in contact with the supporting substrate. We observe a diversity of deposition morphologies that depends on a limited set of operational parameters, mainly ink flow rate, substrate speed and writing density, and also on material properties (e.g., yield-stress). Among these morphologies, one of them does not depend on fluid properties (as long as the fluid displays some yield-stress) and consists of flat films whose thickness is controllable in a significant range, about [Formula: see text] mm, and tunable in real time during printing. We thus demonstrate the ability to print films with thickness gradients and prove that the printing fidelity is mainly due to a competition between yield-stress and capillarity.
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