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Updated: Aug 4, 2025

Observing Islet Function and Islet-Immune Cell Interactions in Live Pancreatic Tissue Slices
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The Extra-Islet Pancreas Supports Autoimmunity in Human Type 1 Diabetes

G L Barlow, C M Schürch, S S Bhate

    Medrxiv : the Preprint Server for Health Sciences
    |March 30, 2023
    PubMed
    Summary

    Researchers investigated immune cell involvement in Type 1 diabetes (T1D) insulitis. They discovered distinct immune cell states within and outside pancreatic islets, revealing coordinated inflammation in T1D pathogenesis.

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