Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

43
Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
43
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

21
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
21
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

14
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
14
Dysrhythmias I: Introduction01:15

Dysrhythmias I: Introduction

22
Dysrhythmias refers to abnormalities in the heart's rhythm. They result from disruptions in the heart's electrical conduction system, which includes the sinoatrial(SA)node, atrioventricular(AV) node, the bundle of His, bundle branches, and Purkinje fibers.Definition and PathophysiologyDysrhythmias result from disorders of impulse formation, impulse conduction, or both. The heart contains specialized cells in the sinoatrial node, atrioventricular node, and the bundle of His and Purkinje fibers...
22
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

1.1K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
1.1K
Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

19
Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
19

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Autonomic Dysfunction in Long COVID Is Distinct From Pure Autonomic Failure.

Journal of the American College of Cardiology·2026
Same author

Test-retest reliability of clinical supine-to-stand tests in patients with postural orthostatic tachycardia syndrome: A cautionary tale.

Heart rhythm·2026
Same author

Letter to the editor regarding "Chronic autonomic symptom burden in long-COVID: a follow-up cohort study."

Clinical autonomic research : official journal of the Clinical Autonomic Research Society·2025
Same author

Minimal Objective Autonomic Dysfunction in Long COVID.

Journal of the American College of Cardiology·2025
Same author

Hydrate to keep the amyloid away.

Journal of Alzheimer's disease : JAD·2025
Same author

Plasma glial fibrillary acidic protein as a biomarker of acute focal brain injury after high-intensity focused ultrasound thalamotomy.

Brain communications·2025

Related Experiment Video

Updated: Aug 4, 2025

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties
08:27

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties

Published on: February 19, 2020

14.2K

Limb myorhythmia treated with chemodenervation: a case report.

Nil Saez-Calveras1, Meredith Bryarly2,3, Meagen Salinas2,3

  • 1University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Therapeutic Advances in Neurological Disorders
|March 30, 2023
PubMed
Summary

Botulinum toxin injections effectively managed limb myorhythmia in a patient unresponsive to conventional treatments. This treatment offered significant symptom reduction and improved quality of life for this rare movement disorder.

Keywords:
botulinum toxincase reportchemodenervationmyorhythmia

More Related Videos

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
08:43

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Published on: August 26, 2021

2.5K
Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
06:13

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain

Published on: March 1, 2024

995

Related Experiment Videos

Last Updated: Aug 4, 2025

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties
08:27

Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties

Published on: February 19, 2020

14.2K
Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
08:43

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Published on: August 26, 2021

2.5K
Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
06:13

Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain

Published on: March 1, 2024

995

Area of Science:

  • Neurology
  • Movement Disorders
  • Chemodenervation Therapy

Background:

  • Limb myorhythmia is a rare movement disorder characterized by slow, rhythmic, involuntary muscle contractions.
  • Management options for myorhythmia are limited, with pharmacologic treatments often showing minimal efficacy.
  • This case highlights a patient with medication-refractory limb myorhythmia following an ankle injury.

Observation:

  • A 30-year-old male presented with persistent, rhythmic tremor in his left foot toes, diagnosed as limb myorhythmia.
  • Electromyography (EMG) confirmed rhythmic activity in the flexor digitorum brevis muscle.
  • Standard medical treatments including muscle relaxants, gabapentin, and levodopa failed to alleviate symptoms.

Findings:

  • EMG-guided injections of incobotulinum toxin A into the affected flexor digitorum brevis muscle were administered.
  • The patient experienced a sustained 50% reduction in movement intensity at 3-month follow-up.
  • Significant improvement in the patient's quality of life was reported post-treatment.

Implications:

  • Botulinum toxin chemodenervation, guided by EMG, presents a viable therapeutic option for focal, medication-refractory limb myorhythmia.
  • This approach offers a targeted treatment strategy for rare movement disorders affecting accessible muscles.
  • Successful palliation suggests potential for broader application in similar challenging myorhythmia cases.